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Two commonly used methods are by specific disease process or a combination of laboratory abnormalities and clinical conditions that arise from the liver disease.Ultimately, the transplantation team takes into account the type of liver disease, the person's blood test results, and the person's health problems in order to determine who is a suitable candidate for transplantation.As techniques in liver surgery have improved, the risk of death in people who donate a part of their liver has dropped to about 1%.The donated liver will be transplanted into the patient.Rejection occurs when the patient's body attacks the new liver.

In children, and in adolescents younger than 18 years, the most common reason for liver transplantation is biliary atresia, which is an incomplete development of the bile ducts.

Local agencies, the Organ Procurement Organizations (OPO), facilitate the identification and procurement of livers for distribution through UNOS.

The United States has been divided into regions to try to fairly distribute this scarce resource.

Many donors are victims of some sort of trauma and have been declared brain dead.

A donor with the right blood type and similar body weight is sought.

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